{"id":555,"date":"2022-10-20T19:54:02","date_gmt":"2022-10-20T11:54:02","guid":{"rendered":"http:\/\/dd863056.alywp100.jshxdt.com.cn\/?p=555"},"modified":"2024-01-23T19:54:43","modified_gmt":"2024-01-23T11:54:43","slug":"%e6%be%b3%e9%97%a8%e5%a4%a7%e5%ad%a6%e7%8e%8b%e6%98%a5%e6%98%8e%e5%9b%a2%e9%98%9f%ef%bc%9a%e9%9d%9e%e6%ba%b6%e5%89%82%e6%b7%ac%e7%81%ab%e5%ae%9e%e7%8e%b0%e5%a4%a9%e7%84%b6%e5%a4%9a","status":"publish","type":"post","link":"https:\/\/www.genetrump.cn\/ch\/%e6%be%b3%e9%97%a8%e5%a4%a7%e5%ad%a6%e7%8e%8b%e6%98%a5%e6%98%8e%e5%9b%a2%e9%98%9f%ef%bc%9a%e9%9d%9e%e6%ba%b6%e5%89%82%e6%b7%ac%e7%81%ab%e5%ae%9e%e7%8e%b0%e5%a4%a9%e7%84%b6%e5%a4%9a\/","title":{"rendered":"\u6fb3\u95e8\u5927\u5b66\u738b\u6625\u660e\u56e2\u961f\uff1a\u975e\u6eb6\u5242\u201c\u6dec\u706b\u201d\u5b9e\u73b0\u5929\u7136\u591a\u7cd6\u76843D\u6253\u5370"},"content":{"rendered":"

\u591a\u7cd6\u4f5c\u4e3a\u4e00\u7c7b\u5929\u7136\u6765\u6e90\u7684\u751f\u7269\u6750\u6599\u5177\u6709\u4e30\u5bcc\u800c\u53c8\u5fae\u5999\u7684\u751f\u7269\u6d3b\u6027\uff0c\u5b83\u4e0d\u4ec5\u80fd\u591f\u7ecf\u7531\u7cd6\u7c7b\u8bc6\u522b\u53d7\u4f53\u00a0(Carbohydrate-recognizing receptor)\u76f4\u63a5\u53d1\u6325\u4f5c\u7528\uff0c\u4e5f\u80fd\u901a\u8fc7\u4e0e\u751f\u957f\u56e0\u5b50\u7684\u52a8\u6001\u7ed3\u5408\uff0c\u8fbe\u5230\u5bf9\u514d\u75ab\u7ec6\u80de\u6d3b\u6027\u95f4\u63a5\u8c03\u8282\u7684\u76ee\u7684\u3002\u4f46\u591a\u7cd6\u6750\u6599\u81ea\u8eab\u7269\u7406\u6027\u8d28\u7684\u4e0d\u8db3\u9650\u5236\u5176\u8fdb\u4e00\u6b65\u7684\u5f00\u53d1\u5229\u7528\u3002\u5c24\u5176\u662f\u57283D\u6253\u5370\u9886\u57df\uff0c\u7531\u4e8e\u6324\u51fa\u5f62\u6210\u7684\u591a\u7cd6\u5fae\u4e1d(filament)\u5185\u90e8\u5206\u5b50\u95f4\u4f5c\u7528\u529b\u5f31\uff0c\u81f4\u4f7f\u5fae\u4e1d\u6c89\u79ef\u5728\u63a5\u6536\u5e73\u53f0\u4e4b\u540e\u4fbf\u8fc5\u901f\u53d1\u751f\u584c\u9677\u3001\u878d\u5408\uff0c\u65e0\u6cd5\u5806\u79ef\u5f62\u6210\u9884\u8bbe\u7684\u4e09\u7ef4\u7ed3\u6784\uff0c\u5df2\u6210\u4e3a\u4e00\u4e2a\u666e\u904d\u7684\u56f0\u6270\u3002\u7eb5\u89c2\u76ee\u524d3D\u6253\u5370\u751f\u7269\u6750\u6599\u53d1\u5c55\u591a\u5e74\uff0c\u53ef\u76f4\u63a5\u7528\u4e8e\u6253\u5370\u7684\u201c\u58a8\u6c34\u201d\u5be5\u5be5\u65e0\u51e0\uff0c\u800c\u57fa\u4e8e\u591a\u7cd6\u7684\u4e5f\u56f4\u7ed5\u5728\u6d77\u85fb\u9178\u94a0\uff08alginate\uff09\u7b49\u5c48\u6307\u53ef\u6570\u7684\u4e00\u4e24\u7c7b\u5206\u5b50\uff0c\u4e14\u5927\u591a\u4f1a\u5728\u6253\u5370\u8fdb\u884c\u9884\u5904\u7406\u3002\u7684\u786e\uff0c\u591a\u7cd6\u6750\u6599\u5f80\u5f80\u9700\u8981\u901a\u8fc7\u5316\u5b66\u4fee\u9970\u6216\u8005\u4e0e\u5176\u5b83\u6750\u6599\u5171\u6df7\u6765\u89e3\u51b3\u5fae\u4e1d\u201c\u5185\u90e8\u201d\u5f3a\u5ea6\u4e0d\u591f\uff0c\u6216\u8005\u6db2\u6001-\u80f6\u6001\u8f6c\u53d8(sol-gel transition)\u6162\u7684\u95ee\u9898\u3002\u7136\u800c\uff0c\u8fd9\u4e9b\u65b9\u5f0f\u4e0d\u53ef\u907f\u514d\u5730\u4f1a\u4e3a\u4f53\u5185\u6d3b\u6027\u7684\u7814\u7a76\u5f15\u5165\u989d\u5916\u53d8\u91cf\uff0c\u6709\u53ef\u80fd\u63a9\u76d6\u4e86\u7cd6\u7ed3\u6784\u81ea\u8eab\u7684\u5fae\u5999\u548c\u7cbe\u786e\u7684\u751f\u7269\u6d3b\u6027\uff0c\u5e76\u4e14\u589e\u52a0\u4e86\u6750\u6599\u5747\u4e00\u6027\u7684\u63a7\u5236\u96be\u5ea6\u3002<\/p>\n

\u6fb3\u95e8\u5927\u5b66\u738b\u6625\u660e\u6559\u6388\u56e2\u961f\u4e00\u76f4\u4ee5\u8461\u7518\u805a\u7cd6\u53ca\u5176\u884d\u751f\u7269\u4e3a\u6a21\u578b\uff0c\u5f00\u53d1\u4e0d\u540c\u79cd\u7c7b\u7684\u514d\u75ab\u6d3b\u6027\u751f\u7269\u6750\u6599\uff1b\u7136\u800c\uff0c\u5374\u56e0\u7cd6\u7c7b\u672c\u8eab\u7684\u201c\u4e0d\u53ef\u6253\u5370\u6027\u201d\uff0c\u65e0\u6cd5\u5c1d\u8bd53D\u6253\u5370\u8fd9\u4e00\u5bf9\u4ed6\u4eec\u7684\u591a\u7cd6\u7814\u7a76\u6765\u8bf4\u201c\u65e2\u6210\u719f\u3001\u53c8\u65b0\u9c9c\u201d\u7684\u5de5\u5177\u3002\u7528\u8bfe\u9898\u8d1f\u8d23\u4eba\u7684\u8bdd\u6765\u8bf4\uff0c\u201c\u5fc3\u548c\u624b\u90fd\u75d2\u75d2\u7684\u201d\uff0c\u4ed6\u4eec\u8fdb\u800c\u51b3\u5b9a\u6df1\u5165\u63a2\u7d22\u4e00\u79cd\u53ef\u4ee5\u4e0d\u901a\u8fc7\u5316\u5b66\u4fee\u9970\u800c\u6253\u5370\u8461\u7518\u805a\u7cd6\u7684\u6280\u672f\uff0c\u5e76\u671f\u671b\u8fd9\u4e00\u6280\u672f\u53ef\u4ee5\u5e94\u7528\u4e8e\u4e0d\u540c\u7ed3\u6784\u3001\u4e0d\u540c\u7406\u5316\u6027\u8d28\u7684\u591a\u7cd6\u6253\u5370\uff0c\u751a\u81f3\u6709\u53ef\u80fd\u63a5\u8fd1\u6216\u6210\u4e3a\u4e00\u79cd\u666e\u9002\u65b9\u6cd5\u3002\u56e2\u961f\u53d7\u91d1\u5c5e\u52a0\u5de5\u8fc7\u7a0b\u4e2d\u7684\u6dec\u706b(quenching)\u5de5\u827a\u542f\u53d1\uff0c\u5f00\u53d1\u4e86\u4e00\u79cd\u76f4\u63a5\u6253\u5370\u5929\u7136\u591a\u7cd6\u6750\u6599\u7684\u975e\u6eb6\u5242\u6dec\u706b(NSQ)\u7684\u6253\u5370\u6280\u672f\u3002\u8be5\u6280\u672f\u5229\u7528\u6eb6\u5242\u4ea4\u6362\u7684\u539f\u7406\uff0c\u7528\u53ef\u4e0e\u6c34\u4e92\u6eb6\uff0c\u4f46\u4e0d\u80fd\u6eb6\u89e3\u591a\u7cd6\u7684\u975e\u6eb6\u5242(non-solvent)\uff0c\u6765\u8bf1\u5bfc\u5fae\u4e1d\u754c\u9762\u53d1\u751f\u8fc7\u9971\uff0c\u8fdb\u800c\u4f7f\u5904\u4e8e\u754c\u9762\u7684\u591a\u7cd6\u53d1\u751f\u56fa\u5316(quenching)\uff0c\u4ece\u800c\u5b9e\u73b0\u201c\u9501\u6c34\u201d(water-locking)\uff0c\u4f7f\u591a\u7cd6\u6750\u6599\u5f62\u72b6\u4fdd\u771f\u5ea6(Shape-fidelity)\u5f97\u5230\u663e\u8457\u63d0\u5347\u3002\u6b64\u5916\uff0c\u7814\u7a76\u56e2\u961f\u4f7f\u7528\u57fa\u4e8eNSQ\u6253\u5370\u7684\u6805\u683c\u652f\u67b6\uff0c\u53d1\u73b0\u5f97\u5230\u7cbe\u7ec6\u52a0\u5de5\u4e4b\u540e\u7684\u591a\u7cd6\u6750\u6599\u80fd\u591f\u5b9e\u73b0\u66f4\u52a0\u7cbe\u786e\u7684\u514d\u75ab\u8c03\u8282\u6d3b\u6027\u3002\u76f8\u5173\u5de5\u4f5c\u8054\u5408\u5357\u4eac\u5927\u5b66\u8463\u78ca\u6559\u6388\u4e0e\u89e3\u653e\u519b\u603b\u533b\u9662\u5b59\u6653\u8273\u6559\u6388\uff0c\u4ee5\u9898\u4e3a\uff1aA \u201cnon-solvent quenching\u201d strategy for 3D printing of polysaccharide scaffolds with immunoregulatory accuracy\u53d1\u8868\u5728Advanced Science\u6742\u5fd7\u4e0a\u3002<\/p>\n

    \n
  1. \u975e\u6eb6\u5242\u7684\u7b5b\u9009\u4e0e\u539f\u7406\u9a8c\u8bc1<\/li>\n<\/ol>\n

    \u7814\u7a76\u8005\u8ba4\u4e3a\u7406\u60f3\u7684\u975e\u6eb6\u5242\u9700\u8981\u5177\u5907\u4ee5\u4e0b\u6761\u4ef6\uff0c\u7b2c\u4e00\uff0c\u754c\u9762\u56fa\u5316\u901f\u5ea6\u5feb\uff0c\u4fdd\u8bc1\u5fae\u4e1d\u5728\u584c\u9677\u524d\u5c31\u901a\u8fc7\u5916\u90e8\u5b9a\u578b\uff0c\u9501\u4f4f\u4e86\u5185\u90e8\u7684\u6c34\uff1b\u7b2c\u4e8c\uff0c\u6eb6\u5242\u7f6e\u6362\u4e4b\u540e\u7684\u5fae\u4e1d\u4e0d\u80fd\u53d1\u751f\u8fc7\u5ea6\u7684\u5f62\u53d8\uff0c\u5426\u5219\u4e0d\u5229\u4e8e\u6253\u5370\u8fc7\u7a0b\u4e2d\u4fdd\u771f\u5ea6\u7684\u7ef4\u6301\u3002\u56e0\u6b64\uff0c\u4ed6\u4eec\u9009\u62e9\u4e865\u79cd\u5177\u6709\u4e0d\u540c\u7406\u5316\u6027\u8d28\u7684\u5929\u7136\u591a\u7cd6\uff0c\u9996\u5148\u5c55\u5f00\u4e86\u5bf9\u5404\u81ea\u6700\u9002\u975e\u6eb6\u5242\u7684\u7b5b\u9009\u3002\u63a5\u4e0b\u6765\uff0c\u56e2\u961f\u4ee5\u76f4\u94fe\u8461\u7518\u805a\u7cd6(GM)\u4e3a\u4f8b\uff0cN,N-\u4e8c\u7532\u57fa\u7532\u9170\u80fa(DMF)\u4e8e\u5b83\u800c\u8a00\u80fd\u591f\u5feb\u901f\u5b9e\u73b0\u8868\u9762\u56fa\u5316\uff0c\u540c\u65f6\u4e0d\u4f1a\u5bfc\u81f4\u5fae\u4e1d\u76f4\u5f84\u7684\u8fc7\u5ea6\u6536\u7f29\uff0c\u56e0\u6b64\u53ef\u4f5c\u4e3aGM\u7684\u9002\u5b9c\u975e\u6eb6\u5242\u3002\u63a5\u6765\u4e0b\uff0c\u4ed6\u4eec\u4ece\u6eb6\u5242\u3001\u975e\u6eb6\u5242\u4e0e\u591a\u7cd6\u6750\u6599\u4eb2\u548c\u6027\u7684\u89d2\u5ea6\u5206\u6790\u4e0d\u540c\u975e\u6eb6\u5242\u662f\u5982\u4f55\u5f71\u54cd\u591a\u7cd6\u76f4\u5f84\u53d8\u5316\u7684\u3002\u56e2\u961f\u501f\u52a9\u4e86\u6eb6\u89e3\u5ea6\u53c2\u6570\u7684\u6982\u5ff5\uff0c\u901a\u8fc7\u8ba1\u7b97\u62df\u5408\uff0c\u53d1\u73b0\u975e\u6eb6\u5242\u7684\u5206\u6563\u6027\u4ee5\u53ca\u6781\u6027\u53ef\u80fd\u662f\u5f71\u54cd\u76f4\u5f84\u53d8\u5316\u7684\u6f5c\u5728\u56e0\u7d20\u3002\u8fdb\u4e00\u6b65\u7684\uff0c\u7814\u7a76\u8005\u901a\u8fc7\u5206\u6790\u5fae\u4e1d\u7684\u5f84\u5411\u7ed3\u6784\uff0c\u89c2\u5bdf\u5230\u5fae\u4e1d\u5f84\u5411\u4e0a\u7531\u5916\u5411\u5185\u5448\u73b0\u51fa\u7531\u81f4\u5bc6\u5230\u758f\u677e\u591a\u5b54\u7684\u7ed3\u6784\u53d8\u5316\uff0c\u8bc1\u5b9e\u4e86\u201c\u9501\u6c34\u201d\u7684\u8bbe\u60f3\u3002<\/p>\n

      \n
    1. NSQ\u6253\u5370\u65b9\u6cd5\u7684\u63a2\u7d22\u4e0e\u666e\u9002\u6027\u8003\u5bdf<\/li>\n<\/ol>\n

      GM\u4f5c\u4e3a\u7814\u7a76\u56e2\u961f\u957f\u671f\u5173\u6ce8\u7684\u591a\u7cd6\uff0c\u56e0\u6b64\u56f4\u7ed5GM\u5c55\u5f00\u4e86\u6253\u5370\u5de5\u827a\u7684\u63a2\u7d22\u3002\u4ed6\u4eec\u4ee5\u6750\u6599\u7684\u6324\u51fa\u6027\u4f5c\u4e3a\u6d53\u5ea6\u9009\u62e9\u7684\u4f9d\u636e\uff0c\u901a\u8fc7\u6d41\u53d8\u6027\u80fd\u7684\u8003\u5bdf\u53d1\u73b0\uff0c\u76f8\u6bd4\u4e8e\u4f20\u7edf\u7684\u6253\u5370\u65b9\u5f0f(CP)\uff0cNSQ\u80fd\u8d4b\u4e88GM\u66f4\u5e7f\u7684\u6253\u5370\u7a97\u53e3\uff0c\u5373\u4f7f\u5728\u8f83\u4f4e\u7c98\u5ea6\u4e0b\uff0c\u4e5f\u80fd\u4fdd\u969c\u6324\u51fa\u7684\u591a\u7cd6\u6eb6\u6db2\u5f62\u6210\u5fae\u4e1d\u800c\u975e\u6db2\u6ef4\u3002\u8fdb\u4e00\u6b65\u7684\uff0c\u7814\u7a76\u8005\u4ee5\u7ecf\u5178\u7684\u6805\u683c\u7ed3\u6784\u4f5c\u4e3a\u6253\u5370\u6a21\u578b\uff0c\u901a\u8fc7\u5916\u89c2\u89c2\u5bdf\u4ee5\u53ca\u53ef\u6253\u5370\u503c(Pr)\u8fdb\u884c\u5b9a\u91cf\uff0c\u53d1\u73b0\u4e94\u79cd\u5929\u7136\u591a\u7cd6\u6750\u6599\u7684\u5f62\u72b6\u4fdd\u771f\u5ea6\u5747\u5f97\u5230\u663e\u8457\u63d0\u5347\uff0c\u4e14\u5177\u5907\u5236\u9020\u590d\u6742\u7ed3\u6784\u7684\u80fd\u529b\u3002\u6b64\u5916\uff0c\u4ed6\u4eec\u8fd8\u53d1\u73b0\uff0c\u652f\u67b6\u5728\u975e\u6eb6\u5242\u4e2d\u80fd\u591f\u957f\u65f6\u95f4\u5730\u5b58\u653e\uff0c\u56e0\u6b64\u589e\u52a0\u4e86NSQ\u652f\u67b6\u5728\u5546\u4e1a\u4ee5\u53ca\u4e34\u5e8a\u5e94\u7528\u4e2d\u7684\u6f5c\u529b\u3002<\/p>\n

        \n
      1. NSQ\u6253\u5370\u591a\u7cd6\u652f\u67b6\u7684\u514d\u75ab\u6d3b\u6027\u8003\u5bdf<\/li>\n<\/ol>\n

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        4\uff0eNSQ\u8d4b\u4e88\u591a\u7cd6\u5dee\u5f02\u6027\u8c03\u63a7\u539f\u56e0\u63a2\u7a76\u53ca\u9a8c\u8bc1<\/p>\n

        \u4e0d\u540c\u95f4\u8ddd\u7684\u5fae\u4e1d\u6240\u5e26\u6765\u7684\u5c40\u90e8\u529b\u5b66\u6027\u8d28\u7684\u5dee\u5f02\u53ef\u80fd\u4f1a\u7ecf\u7531\u673a\u68b0\u4f20\u5bfc\u901a\u8def(mechanotransduction pathway)\u5e26\u6765\u4e0d\u540c\u7684\u514d\u75ab\u6548\u5e94\u3002\u7814\u7a76\u8005\u5206\u522b\u5bf9\u5c40\u90e8\u6a21\u91cf\u8fdb\u884c\u4e86\u5f52\u4e00\u5316\u8ba1\u7b97\u4ee5\u53ca\u5bf9\u751f\u7269\u529b\u5b66\u901a\u8defYAP\/TAZ\u4e2d\u76ee\u6807\u57fa\u56e0\u7684\u8868\u8fbe\u6c34\u5e73\u8fdb\u884c\u5206\u6790\uff0c\u53d1\u73b0\u4e24\u8005\u5177\u6709\u76f8\u4f3c\u7684\u529b\u5b66\u6027\u8d28\uff0c\u5e76\u4e14\u76f8\u5173\u57fa\u56e0\u7684\u8868\u8fbe\u6c34\u5e73\u65e0\u663e\u8457\u6027\u5dee\u5f02\uff0c\u7531\u6b64\u6392\u9664\u4e86\u751f\u7269\u529b\u5b66\u7684\u56e0\u7d20\uff1b\u57fa\u56e0\u6d4b\u5e8f\u7684\u7ed3\u679c\u8868\u660e\uff0c\u7cd6\u7c7b\u8bc6\u522b\u53d7\u4f53\u4e2d\uff0cTLR2\u7684\u8868\u8fbe\u6c34\u5e73\u5728\u7ec4\u95f4\u6709\u8f83\u5927\u7684\u5dee\u5f02\uff0c\u7814\u7a76\u56e2\u961f\u731c\u6d4b\u8be5\u53d7\u4f53\u53ef\u80fd\u5728\u5bbf\u4e3b\u8bc6\u522b\u4e0d\u540c\u7ed3\u6784\u652f\u67b6\u4e2d\u53d1\u6325\u7740\u91cd\u8981\u4f5c\u7528\uff0c\u56e0\u6b21\uff0c\u4ed6\u4eec\u901a\u8fc7Tlr2-\/-\u6572\u9664\u5c0f\u9f20\u8fdb\u884c\u9a8c\u8bc1\uff0c\u53d1\u73b0\u4e4b\u524d\u89c2\u5bdf\u5230\u7684\u7ec4\u95f4\u5dee\u5f02\u90fd\u6d88\u9664\u4e86\uff0c\u8ba4\u4e3aTLR2\u7684\u5dee\u5f02\u6027\u6fc0\u6d3b\u53ef\u80fd\u662f\u9020\u6210\u4e0a\u8ff0\u7ed3\u679c\u7684\u5173\u952e\u539f\u56e0\u3002\u8fdb\u4e00\u6b65\u7684\uff0c\u4e3a\u4e86\u63a2\u7a76\u4fee\u9970\u540e\u7684\u591a\u7cd6\u6750\u6599\u662f\u5426\u80fd\u540c\u6837\u5e26\u6765\u5dee\u5f02\u6027\u7684\u514d\u75ab\u8c03\u63a7\uff0c\u7814\u7a76\u8005\u5c06GM\u8fdb\u884c\u4e59\u9170\u5316\u4fee\u9970(GMAC)\u4f7f\u5176\u80fd\u591f\u901a\u8fc7\u4f20\u7edf\u65b9\u5f0f\u8fdb\u884c\u6253\u5370\u3002\u7ed3\u679c\u8868\u660e\uff0c\u540c\u6837\u51e0\u4f55\u7ed3\u6784\u4e0b\uff0c\u5e76\u672a\u89c2\u5bdf\u5230\u5728NSQ\u6253\u5370\u652f\u67b6\u4e2d\u51fa\u73b0\u7684\u5dee\u5f02\u3002\u76f8\u53cd\uff0c\u5177\u6709\u4e0d\u540c\u5f62\u8c8c\u7684GMAC\u652f\u67b6\uff0c\u5747\u5c55\u73b0\u5f3a\u70c8\u4e14\u76f8\u4f3c\u7684\u708e\u75c7\u53cd\u5e94\uff0c\u7814\u7a76\u8005\u731c\u6d4b\uff0c\u5267\u70c8\u7684\u514d\u75ab\u53cd\u5e94\u53ef\u80fd\u662f\u63a9\u76d6\u51e0\u4f55\u7ed3\u6784\u8bf1\u5bfc\u5929\u7136\u591a\u7cd6\u5dee\u5f02\u6027\u8c03\u63a7\u7684\u6f5c\u5728\u539f\u56e0\u3002<\/p>\n

        \u7efc\u4e0a\u6240\u8ff0\uff0cNSQ\u521b\u65b0\u6027\u5730\u5c06\u201c\u6dec\u706b\u201d\u7684\u6982\u5ff5\u4ece\u91d1\u5c5e\u52a0\u5de5\u5f15\u5165\u5230\u4e86\u5929\u7136\u591a\u7cd6\u6253\u5370\uff0c\u8be5\u65b9\u5f0f\u6709\u5982\u4e0b\u7279\u70b9\uff1a1\uff09\u4e00\u5b9a\u7a0b\u5ea6\u4e0a\u62d3\u5c55\u4e86\u591a\u7cd6\u6750\u6599\u6253\u5370\u7a97\u53e3\u7684\u8fb9\u754c\uff1b2\uff09\u6709\u5229\u4e8e\u591a\u7cd6\u652f\u67b6\u7684\u957f\u671f\u4fdd\u5b58\uff1b3\uff09\u901a\u8fc7\u63d0\u5347\u5929\u7136\u591a\u7cd6\u6750\u6599\u6253\u5370\u7684\u4fdd\u771f\u5ea6\uff0c\u8d4b\u4e88\u591a\u7cd6\u6750\u6599\u7269\u7406\u624b\u6bb5\u8bf1\u5bfc\u7684\u5fae\u5999\u8c03\u63a7\u4f5c\u7528\uff1b4\uff09\u4e0d\u6d89\u53ca\u5316\u5b66\u4fee\u9970\u6216\u5f15\u5165\u5176\u4ed6\u6750\u6599\uff0c\u6700\u5927\u7a0b\u5ea6\u5730\u4fdd\u7559\u4e86\u591a\u7cd6\u56fa\u6709\u751f\u7269\u6d3b\u6027\uff0c\u56e0\u800c\u907f\u514d\u4e86\u5316\u5b66\u4fee\u9970\u5e26\u6765\u7684\u6f5c\u5728\u5f71\u54cd\u3002<\/p>\n

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